In Sickness & In Health

In Sickness & In Health
Greg's Family Pedigree
In Greg's family pedigree each generation has one of the two diseases. And in some cases more then one person in that generation has the disease. Myotonic Dystrophy is more dominant in Greg's family then Hemophilia. Although hemophilia is a more dominant gene over the recessive myotonic dystrophy.

Olga's Family Pedigree
However, in Olga's family pedigree myotonic dystrophy never occurs, but hemophilia is very dominant throughout the generations in her family. Which could possibly result in Greg and her's children being positive for Hemophilia.

Greg and Olga, are a couple that went to a genetic counselor. The couple wanted to conceive children, but were afraid to because they had the Factor VIII deficiency, or Hemophillia in there heritage. Both Greg and Olga were terrified that their children could possibly be born with a genetic disease. Both sides of their families carried the disease and it seemed obvious to the couple that no matter what, their children could inhabit this disease.

Dominant Diseases
Although we had been studying genetic deficiencies, this post thanks to the website as well, taugh me alot about genetic diseases. I learned that autosomal recessive diseases skip generations, while autosomal dominant disease don't skip generations. Autosomal recessive diseases are when one mutated allele and one normal gene come together and form. There's a 50% chance of the disease being transmitted. Even if the disease isn't dominant, every child infected will be carriers. In all cases its either the father or the mother who is carrying the disease that has been transmitted.  


Recessive Diseases
Recessive diseases are never inherited directly because recessive diseases are only inherited by the y chromosome. Sex linked genes, can be displayed in men, but not in women, they can only be carriers for the disease. In Greg and Olga's case they both could be a carrier  of the disease, due to the fact that multiple people in their families have the disease. Greg has a higher rate of being a carrier, which can result in him passing this gene onto his sons. However his possible daughters would only become carriers. His daughters could become carriers and easily pass it on to their possible children in the next generation. Genetics is constantly changing, from the smallest ideas to the big picture, but one thing is for certain the advancements made in the future will be those worth remembering!